This “corrects” the stem cells, which are then injected back into the child. Then, a healthy gene for immune cells is inserted into the stem cells in the laboratory. Gene therapy involves taking the stem cells from the child's bone marrow. Gene therapy is another option to cure SCID. If a sibling is not an option, parents or unrelated donors may be able to donate their stem cells. Research shows that when the stem cell donor is a sibling, outcomes are better. A stem cell transplant involves transferring stem cells from a healthy person to the person with SCID. Most children with SCID will need a stem cell transplant, which may provide them with a working immune system and a cure.
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